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1

Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy

Peltoniemi, Marko A., Hagelberg, Nora M., Olkkola, Klaus T., Saari, Teijo I.

Journal:

Clinical Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 725 KB

english, 2016

2

Effect of dexmedetomidine and midazolam on human performance and mood

M. J. Mattila, M. E. Mattila, K. T. Olkkola, H. Scheinin

Journal:

European Journal of Clinical Pharmacology

Year:

1991

Language:

english

File:

PDF, 705 KB

english, 1991

3

Diclofenac pharmacokinetic meta-analysis and dose recommendations for surgical pain in children aged 1–12 years

Joseph F. Standing, Dick Tibboel, Reijo Korpela, Klaus T. Olkkola

Journal:

Pediatric Anesthesia

Year:

2011

Language:

english

File:

PDF, 293 KB

english, 2011

4

Predictive equations over-estimate the resting energy expenditure in amyotrophic lateral sclerosis patients who are dependent on invasive ventilation support

Waltteri Siirala, Klaus T Olkkola, Tommi Noponen, Arno Vuori, Riku Aantaa

Journal:

Nutrition & Metabolism

Year:

2010

Language:

english

File:

PDF, 351 KB

english, 2010

5

Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174

K.-M. Kaukonen, K. T. Olkkola, P. J. Neuvonen

Journal:

European Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 282 KB

english, 1998

6

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice

Hukkinen, Sanna K., Varhe, Anu, Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 430 KB

english, 1995

7

Paediatric cardiac arrest and resuscitation provided by physician-staffed emergency care units

P. SUOMINEN, R. KORPELA, M. KUISMA, T. SILFVAST, K. T. OLKKOLA

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1997

Language:

english

File:

PDF, 481 KB

english, 1997

8

Isobaric bupivacaine via spinal catheter for hip replacement surgery: ED50 and ED95 dose determination

A. Sell, K. T. Olkkola, J. Jalonen, R. Aantaa

Journal:

Acta Anaesthesiologica Scandinavica

Year:

2006

Language:

english

File:

PDF, 96 KB

english, 2006

9

Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia

M. Silvanto, E. Munsterhjelm, S. Savolainen, P. Tiainen, T. Niemi, O. Ylikorkala, H. Scheinin, K. T. Olkkola

Journal:

Acta Anaesthesiologica Scandinavica

Year:

2007

Language:

english

File:

PDF, 642 KB

english, 2007

10

Fentanyl for breakthrough cancer pain – what’s new?

Nora M. Hagelberg, Klaus T. Olkkola

Journal:

Year:

2010

Language:

english

File:

PDF, 76 KB

english, 2010

11

The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects.

R Poyhia, T Seppala, KT Olkkola, E Kalso

Journal:

British Journal of Clinical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

12

Pharmacokinetics of Intravenous Paracetamol in Elderly Patients

Dr Antti Liukas, Kristiina Kuusniemi, Riku Aantaa, Petri Virolainen, Mikko Niemi, Pertti J. Neuvonen, Klaus T. Olkkola

Journal:

Clinical Pharmacokinetics

Year:

2011

Language:

english

File:

PDF, 196 KB

english, 2011

13

Is the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent?

Waltteri Siirala, Riku Aantaa, Klaus T Olkkola, Tarja Saaresranta…

Journal:

BMC Palliative Care

Year:

2013

Language:

english

File:

PDF, 221 KB

english, 2013

14

Clinical Pharmacokinetics and Pharmacodynamics of Opioid Analgesics in Infants and Children

Olkkola, Klaus T., Hamunen, Katri, Maunuksela, Eeva-Liisa

Journal:

Clinical Pharmacokinetics

Year:

1995

Language:

english

File:

PDF, 1.78 MB

english, 1995

15

Effect of oral activated charcoal on the absorption and elimination of drugs and toxins in humans

Journal:

Réanimation Urgences

Year:

1993

Language:

english

File:

PDF, 452 KB

english, 1993

16

Oral Activated Charcoal in the Treatment of Intoxications

Dr Pertti J. Neuvonen,Klaus T. Olkkola

Journal:

Year:

1988

Language:

english

File:

PDF, 3.50 MB

english, 1988

17

Enhancement of GABAergic Activity: Neuropharmacological Effects of Benzodiazepines and Therapeutic Use in Anesthesiology

Saari, T. I., Uusi-Oukari, M., Ahonen, J., Olkkola, K. T.

Journal:

Pharmacological Reviews

Year:

2011

Language:

english

File:

PDF, 921 KB

english, 2011

18

Feasibility and Cardiac Safety of Inhaled Xenon in Combination With Therapeutic Hypothermia Following Out-of-Hospital Cardiac Arrest*

Arola, Olli J., Laitio, Ruut M., Roine, Risto O., Grönlund, Juha, Saraste, Antti, Pietilä, Mikko, Airaksinen, Juhani, Perttilä, Juha, Scheinin, Harry, Olkkola, Klaus T., Maze, Mervyn, Laitio, Timo T.

Journal:

Critical Care Medicine

Year:

2013

Language:

english

File:

PDF, 9.93 MB

english, 2013

19

Pharmacokinetics of Ropivacaine in Patients with Chronic End-stage Liver Disease

Jokinen, Mika J., Neuvonen, Pertti J., Lindgren, Leena, H??ckerstedt, Krister, Sj??vall, Jan, Breuer, Olof, Askemark, Yvonne, Ahonen, Jouni, Olkkola, Klaus T.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.23 MB

english, 2007

20

A Comparison of Remifentanil and Alfentanil for Use with Propofol in Patients Undergoing Minimally Invasive Coronary Artery Bypass Surgery

Ahonen, Jouni, Olkkola, Klaus T., Verkkala, Kalervo, Heikkinen, Leo, J??rvinen, Antero, Salmenper??, Markku

Journal:

Anesthesia & Analgesia

Year:

2000

Language:

english

File:

PDF, 156 KB

english, 2000

21

Relationship of Edoxaban Plasma Concentration and Blood Coagulation in Healthy Volunteers Using Standard Laboratory Tests and Viscoelastic Analysis

HavrdovÃ¡, Martina, Saari, Teijo I., Jalonen, Jouko, Peltoniemi, Marko, Kurkela, Mika, Vahlberg, Tero, Tienhaara, Anri, Backman, Janne T., Olkkola, Klaus T., Schramko, Alexey

Journal:

Journal of Clinical Pharmacology

Year:

2020

File:

PDF, 1.66 MB

2020

22

St John’s wort greatly reduces the concentrations of oral oxycodone

Tuija H. Nieminen, Nora M. Hagelberg, Teijo I. Saari, Mikko Neuvonen, Kari Laine, Pertti J. Neuvonen, Klaus T. Olkkola

Journal:

European Journal of Pain

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

23

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam

SAARI, T, LAINE, K, LEINO, K, VALTONEN, M, NEUVONEN, P, OLKKOLA, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 340 KB

english, 2006

24

Voriconazole, but not terbinafine, markedly reduces alfentanil clearance and prolongs its half-life

SAARI, T, LAINE, K, LEINO, K, VALTONEN, M, NEUVONEN, P, OLKKOLA, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

25

Clarithromycin, a potent inhibitor of CYP3A, greatly increases exposure to oral S-ketamine

Nora M. Hagelberg, Marko A. Peltoniemi, Teijo I. Saari, Kaisa J. Kurkinen, Kari Laine, Pertti J. Neuvonen, Klaus T. Olkkola

Journal:

European Journal of Pain

Year:

2010

Language:

english

File:

PDF, 167 KB

english, 2010

26

Early continuous invasive blood pressure monitoring during resuscitation attempt in human: Comparison of currently recommended and alternative compression depths

M. Sainio, S. Hoppu, H. Huhtala, J. Eilevstjønn, K.T. Olkkola, J. Tenhunen

Journal:

Year:

2010

Language:

english

File:

PDF, 88 KB

english, 2010

27

Effect of rifampin and tobacco smoking on the pharmacokinetics of ropivacaine

JOKINEN, M, OLKKOLA, K, AHONEN, J, NEUVONEN, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

2001

Language:

english

File:

PDF, 686 KB

english, 2001

28

Rifampin drastically reduces plasma concentrations and effects of oral midazolam

Backman, Janne T., Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 692 KB

english, 1996

29

The effect of ingestion time interval on the interaction between itraconazole and triazolam

Neuvonen, Pertti J., Varhe, Anu, Olkkola, Klaus T.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 576 KB

english, 1996

30

Diltiazem enhances the effects of triazolam by inhibiting its metabolism*

Varhe, Anu, Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 631 KB

english, 1996

31

Itraconazole increases plasma concentrations of quinidine*

Kaukonen, Kirsi-Maija, Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 765 KB

english, 1997

32

Pharmacokinetics and ventilatory effects of oxycodone before and after liver transplantation*

Tallgren, Minna, Olkkola, Klaus T., Seppälä, Timo, Höckerstedt, Krister, Lindgren, Leena

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 701 KB

english, 1997

33

Triazolam is ineffective in patients taking rifampin

Villikka, Kirsti, Kivistö, Kari T., Backman, Janne T., Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 622 KB

english, 1997

34

Itraconazole greatly increases plasma concentrations and effects of felodipine

Jalava, Kirsi-Maija, Olkkola, Klaus T., Neuvonen, Pertti J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 561 KB

english, 1997

35

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone*

Heiskanen, Tarja, Olkkola, Klaus T., Kalso, Eija

Journal:

Clinical Pharmacology & Therapeutics

Year:

1998

Language:

english

File:

PDF, 757 KB

english, 1998

36

Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam

PALKAMA, V, AHONEN, J, NEUVONEN, P, OLKKOLA, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

1999

Language:

english

File:

PDF, 106 KB

english, 1999

37

Utstein style reporting of in-hospital paediatric cardiopulmonary resuscitation

P. Suominen, K.T. Olkkola, V. Voipio, R. Korpela, R. Palo, J. Räsänen

Journal:

Year:

2000

Language:

english

File:

PDF, 163 KB

english, 2000

38

Impact of age, submersion time and water temperature on outcome in near-drowning

P. Suominen, C. Baillie, R. Korpela, S. Rautanen, S. Ranta, K.T. Olkkola

Journal:

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

39

Does water temperature affect outcome of nearly drowned children

Pertti K Suominen, Reijo E Korpela, Tom G.O Silfvast, Klaus T Olkkola

Journal:

Year:

1997

Language:

english

File:

PDF, 62 KB

english, 1997

40

A large simple randomized trial of rocuronium versus succinylcholine in rapid-sequence induction of anaesthesia along with propofol

J. I. Andrews, N. Kumar, R. H. G. Van Den Brom, K. T. Olkkola, G. J. Roest, P. M. C. Wright

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

41

Paracetamol – misused good old drug?

R. Korpela, K. T. Olkkola

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

42

Interaction between fluconazole and midazolam in intensive care patients

J. Ahonen, K. T. Olkkola, A. Takala, P. J. Neuvonen

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1999

Language:

english

File:

PDF, 133 KB

english, 1999

43

Stereoselective pharmacokinetics of ketorolac in children, adolescents and adults

K. Hamunen, E.-L. Maunuksela, J. Sarvela, R. E. S. Bullingham, K. T. Olkkola

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1999

Language:

english

File:

PDF, 129 KB

english, 1999

44

Comparison of rocuronium and suxamethonium for use during rapid sequence induction of anaesthesia

K. C. McCourt, L. Salmela, R. K. Mirakhur, M. Carroll, M.-T. Mäkinen, M. Kansanaho, C. Kerr, G. J. Roest, K. T. Olkkola

Journal:

Year:

1998

Language:

english

File:

PDF, 392 KB

english, 1998

45

Fluconazole, but not terbinafine, enhances the effects of triazolam by inhibiting its metabolism

ANU VARHE, KLAUS T. OLKKOLA, PERTTI J NEUVONEN

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 330 KB

english, 1996

46

Effect of nitrous oxide on cisatracurium infusion demands: a randomized controlled trial

Hanna L Illman, Heikki MJ Antila, Klaus T Olkkola

Journal:

BMC Anesthesiology

Year:

2010

Language:

english

File:

PDF, 321 KB

english, 2010

47

Quality of CPR has little impact on cerebral oximetry during in-hospital cardiac arrest – preliminary data from three case reports

M Sainio, S Hoppu, KT Olkkola, J Tenhunen

Journal:

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Year:

2009

Language:

english

File:

PDF, 93 KB

english, 2009

48

A pharmacokinetic interaction between roxithromycin and midazolam

J. T. Backman, K. Aranko, J. -J. Himberg, K. T. Olkkola

Journal:

European Journal of Clinical Pharmacology

Year:

1994

Language:

english

File:

PDF, 506 KB

english, 1994

49

Steady state pharmacokinetics of piroxicam in children with rheumatic diseases

A.-L. Mäkelä, K. T. Olkkola, M. J. Mattila

Journal:

European Journal of Clinical Pharmacology

Year:

1991

Language:

english

File:

PDF, 238 KB

english, 1991

50

Pharmacokinetics of intravenous diclofenac sodium in children

R. Korpela, K. T. Olkkola

Journal:

European Journal of Clinical Pharmacology

Year:

1990

Language:

english

File:

PDF, 299 KB

english, 1990